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56) Substrate-Induced Cooperative Ionic Catalysis: Difunctionalization 2 of Indole Derivatives Employing Dimethyl Carbonate
Sangita Dattatray Shinde, Ashik Chhetri, Sayak Ghosh, Anusri Debnath, Pooja Joshi, DineshKumar*
Journal of Organic Chemistry 2024, ASAP
55) Selective [3 + 2] C–H/C–H Alkyne Annulation via Dual (Distal) C(β, δ)–H Bond Activation Relay: A Novel Therapeutic Quinazolone-Tethered Benzofulvenes for Oral Cancer
Dinesh Parshuram Satpute, Garvita Narang, Harshal Joshi, Divita Kumar, Sangita Dattatray Shinde, Shyam Kumar Lokhande, Priyanka Patel Vatsa, Vinal Upadhyay, Shivkanya Madhavrao Bhujbal, Amit Mandoli,* Dinesh Kumar*
54) Sustainable C–H methylation employing dimethyl carbonate
Sangita Dattatray Shinde, Garvita Narang, Gargee Mahendra Mahajan, Dinesh Kumar*
Journal of Organic Chemistry 2024, ASAP
53) A Heterocycle-tethered benzofulvene compound and a process of preparation thereo
Indian Patent application Number 202421073889
52) Identification and characterization of GSK-9089 metabolites through high resolution-mass spectrometry based in vitro and in vivo rat biological sample analysis
Manish Kumar Sharma, Ravi P. Shah, Dinesh Kumar, Pinaki Sengupta*
Journal of Chromatography B 2024, 1244, 124242
51) Ionic-molecular organocatalysis enabling allylic amination reactions
Shyam Kumar Lokhande, Gargi Nikhil Vaidya, Ashwini Venkatesh, Vaidehi DeepakKumar Patel, Pooja Joshi, Deep Rohan Chatterjee, Dinesh Kumar*
Cell Rep. Phys. Sci. 2024, 5, 101868
50) An integrative sustainability assessment of the Tsuji–Trost reaction simulating allylic amination under non-conventional (vs. conventional) conditions
Sangita Dattatray Shinde, Gargi Nikhil Vaidya, Shyam Kumar Lokhande, Anil Shaha, Ramesh Hiralal Choudhary, Dinesh Kumar*
49) PATENT GRANTED
Green process for the synthesis of Flunarizine
Inventors: Dinesh Kumar, Gargi Nikhil Vaidya, Mithilesh Nagpure
PATENT No.: 448254, Date of Grant: 30/08/2023
Filing No.: 202021024185, Date of Filing: 09/06/2020
Territory: INDIA
48) Ultra-high-performance liquid chromatography–quadrupole time of flight tandem mass spectrometry based in vitro metabolite profiling of DK-GV-04P, a novel anticancer molecule under drug discovery
Deeki Doma Sherpa, Amit Kumar Sahu, Tarang Jadav, Niraj Rajput, Gargi Nikhil Vaidya, Dinesh Kumar,* Pinaki Sengupta*
Biomed. Chromatogr. 2023, 38, e5806
47) Discovery of fluorinated 2‑Styryl 4(3H)-quinazolinone as potential therapeutic hit for oral cancer
Dinesh Parshuram Satpute, Urjita Shirwadkar, Anil Kumar Tharalla, Sangita Dattatray Shinde, Gargi Nikhil Vaidya, Swarali Joshi, Priyanka Patel Vatsa, Alok Jain, Abhishek Singh, Rachana Garg*, Amit Mandoli*, Dinesh Kumar,*
Bioorg. Med. Chem. 2023, 18, 117193
46) pi-Bond Directed C-2 Amination of Indoles: Catalysis Development, Mechanistic Investigation, and Substrate Scope
Sandeep R. Vemula, Dinesh Kumar,* Gregory R. Cook*
Submitted, (ChemRxiv, 2022)
45) Domino synthesis of functionalized pyridine carboxylates under gallium catalysis: Unravelling the reaction pathway and the role of the nitrogen source counter anion
Dinesh Kumar, Himanshu Sharma, Nirjhar Saha, and Asit K. Chakraborti*
Chem Asian J. 2022, 17, e202200304
44) PATENT GRANTED
Carbonate browsing technology-enabled allylic amination using allyl alcohols under nickel catalysis
Inventors: Dinesh Kumar, Gargi Nikhil Vaidya
PATENT No.: 402617, Date of Grant: 29/07/2022
Filing No.: 202021016956, Date of Filing: 20/04/2020
Territory: INDIA
43) Computational Biology of BRCA2 in Male Breast Cancer, Through Prediction of Probable nsSNPs, and Hit Identification
Sangita Dattatray Shinde, Dinesh Parshuram Satpute, Santosh Kumar Behera,* Dinesh Kumar*
ACS Omega, 2022, 7, 30447–3046
42) Water-enabled, nickel-catalyzed highly chemoselective C-allylation of (NH)-indoles employing alcohols
Gargi Nikhil Vaidya, Shyam Kumar Lokhande, Sangita Dattatray Shinde, Dinesh Parshuram Satpute, Garvita Narang and Dinesh Kumar*
Green Chem. 2022, 24, 4921-4927
41) ‘In-water’, nickel-catalyzed mild preparation of allylic amines employing alcohols: Application to ‘all-water’ synthesis of pharmaceuticals
Gargi N. Vaidya, Ramesh Hiralal Choudhary, Mithilesh Nagpure, Shyam Kumar Lokhande, Pooja Rana, Dinesh Kumar*
Green Chem. 2022, 24, 3977-3984 (selected as a 2022 HOT Article)
40) Organic Reactions in Aqueous Media Catalyzed by Nickel
Dinesh Parshuram Satpute, Gargi N. Vaidya, Shyam Kumar Lokhande, Sangita Dattatray Shinde, Shivkanya Bhujbal, Deep Rohan Chatterjee, Pooja Rana, V. Ashwini, Mithilesh Nagpure, Dinesh Kumar*
Green Chem. 2021, 23, 6273-6300
39) A mechanistic explanation on the degradation behavior of flibanserin for identification and characterization of its potential degradants using LC-DAD/ESI/APCI-Q-TOF-MS/MS
Manish Kumar Sharma, Komal Pandey, Ravi P. Shah, Dinesh Kumar, Pinaki Sengupta*
Microchem. J. 2021, 167, 106282
38) Borrowing Carbonate-Enabled Allylic Amination Reactions under Additive- and Reductant-Free Nickel Catalysis Employing Allylic Alcohols
Gargi Nikhil Vaidya, Mithilesh Nagpure, Dinesh Kumar*
ACS Sustain. Chem. Eng. 2021, 9, 4, 1846
37) The Rise and Fall of Hydroxychloroquine (HCQ) in COVID Era: Therapeutic Journey and Synthetic Progress
Gargi Nikhil Vaidya, Ashwini V., Deep Rohan Chatterjee, Pooja Rana, Mithilesh Nagpure, Dinesh Parshuram Satpute, Kiran Kalia,* Dinesh Kumar*
Submitted, ChemRxiv, 2022
36) Computational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir
Santosh Kumar Behera, Nazmina Vhora, Darshan Contractor, Amit Shard*, Dinesh Kumar*, Kiran Kalia*, Alok Jain*
Sci. Rep. 2021, 11, 7307
35) Paradigm shift of “classical” HDAC inhibitors to “hybrid” HDAC inhibitors in therapeutic interventions
Gargi Nikhil Vaidya, Pooja Rana, Ashwini Venkatesha, Deep Rohan Chatterjee, Darshan Contractor, Dinesh Parshuram Satpute, Mithilesh Nagpure, Alok Jain, Dinesh Kumar*
Eur. J. Med. Chem. 2020, 209, 112844
34) Micellar catalysis enabled synthesis of indolylbenzothiazoles and their functionalization via Mn(II)-catalyzed C2–H amination using pyridones
Sanjeev Kumar, Dinesh Parshuram Satpute, Gargi Nikhil Vaidya, Mithilesh Nagpure, Shyam Kumar, Lokhande, Deepak Meena, Dinesh Kumar*
Tetrahedron Lett. 2020, 61, 152017
33) Structure Ligation Relationship of amino acids for the selective indole C−H arylation reaction: L‐Aspartic acid as sustainable alternative of phosphine ligands
Shyam Kumar Lokhande, Gargi Nikhil Vaidya, Dinesh Parshuram Satpute, Ashwini Venkatesh, Sanjeev Kumar, and Dinesh Kumar*
Adv. Syn. Catal. 2020, 362, 2857-2863
32) Structure Ligation Relationship of amino acids for the amination cross-coupling reactions
Gargi Nikhil Vaidya, Arif Khan, Sanjeev Kumar Lokhande, and Dinesh Kumar
J. Org. Chem. 2019, 84, 5, 3004–3010
31) A micellar catalysis strategy applied to the Pd-catalyzed C–H arylation of indoles in water
Gargi Nikhil Vaidya, Sneha Fiske, Hansa Verma, Shyam Kumar Lokhande, and Dinesh Kumar*
Green Chem. 2019, 21, 1448-1454
30) Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook, “Bismuth-catalyzed green protocol for the synthesis of 2-substituted quinazolinones,” Tetrahedron Lett., 2018, 59, 3801-3805.
29) Dinesh Kumar, Sandeep Reddy Vemula, Narayanaganesh Balasubramanian, and Gregory R. Cook, “Indium-mediated stereoselective allylation,” Acc. Chem. Res., 2016, 49, 2169-2178.
28) Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, “Merging C–H Bond Functionalization with Amide Alcoholysis: En Route to 2-Aminopyridines,” ACS Catal., 2016, 6, 3531-353.
27) Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook, “Palladium-catalyzed allylic amidation with N-heterocycles via sp3 C-H oxidation,” ACS Catal., 2016, 6, 5295-5301.
26) Dinesh Kumar, Sandeep R. Vemula, and Gregory R. Cook, “Recent advances in catalytic synthesis of α-ketoamides,” ACS Catal., 2016, 6, 4920-4945.
25) Pradeep S. Jadhavar, Tejas M. Dhameliya, Maulikkumar D. Vaja, Dinesh Kumar, Jonnalagadda Padma Sridevi, Perumal Yogeshwari, Dharmarajan Sriram, and Asit K. Chakraborti* “Synthesis, biological evaluation, and structure-activity relationship of 2-styrylquinazolones as anti-tubercular agents,” Bioorg. Med. Chem. Lett., 2016, 11, 2663-2669.
24) Dinesh Kumar, Sandeep Reddy Vemula, and Gregory R. Cook, “Highly chemo- and regioselective allylic substitution with tautomerizable heteroarenes,” Green Chem., 2015, 17, 4300-4306.
23) Babita Tanwar, Priyank Purohit, Banothu Naga Raju, Dinesh Kumar, Damodara N. Kommi, and Asit K. Chakraborti, “An “all-water” strategy for regiocontrolled synthesis of 2-aryl quinoxalines," RSC Adv., 2015, 5, 11873-11883.
22) Sandeep Reddy Vemula, Dinesh Kumar, and Gregory R. Cook, “N-Boc-glycine-assisted indium-mediated allylation reaction: A sustainable approach,” Tetrahedron Lett., 2015, 56, 3322-3325.
21) Amreen Mughal, Dinesh Kumar, and Ajit Vikram “Effects of Thiazolidinediones on metabolism and cancer: Relative influence of PPARγ and IGF-1 signaling,” Eur. J Pharmacol., 2015, 768, 217-225.
20) Babita Tanwar, Dinesh Kumar, Asim Kumar, Mohammad Mohsin Qadri, Md. Imam Ansari, and Asit K. Chakraborti, “Friedländer annulation: Scope and limitations of metal salt Lewis acid catalysts in selectivity control for the synthesis of functionalized quinolines,” New J. Chem., 2015, 39, 9824-9833.
19) Dinesh Kumar, Mohammad Mohsin Qadri, Md. Imam Ansari, Asim Kumar, and Asit K. Chakraborti, “In(OTf)3-Catalyzed synthesis of 2-styryl quinolines: Scope and limitations of metal Lewis acids for tandem Friedlander annulation-Knoevenagel condensation,” RSC Adv., 2015, 5, 2920-2927.
18) Dinesh Kumar, Pradeep S. Jadhavar, Manesh Nautiyal, Himanshu Sharma, Prahlad K. Meena, Legesse Adane, Sahaj Pancholia, and Asit K. Chakraborti, “Convenient synthesis of 2,3-disubstituted quinazolin-4(3H)-ones and 2-styryl-3-substituted quinazolin-4(3H)-ones: Applications towards the synthesis of drugs,” RSC Adv., 2015, 5, 30819-30825.
17) Dinesh Kumar, Mukesh Sonawane, Brahmam Pujala, Varun K. Jain, Srikant Bhagat, and Asit K. Chakraborti “Supported protic acid-catalyzed synthesis of 2,3-disubstituted thiazolidin-4- one: enhancement of the catalytic potential of protic acid by adsorbtion on solid support,” Green Chem., 2013, 15, 2872-2884.
16) Damodara N. Kommi, Dinesh Kumar, and Asit K. Chakraborti, “All water chemistry for a concise total synthesis of the anti-anginal drug (RS), (R), and (S)-ranolazine,” Green Chem., 2013, 15, 756–767.
15) Damodara N. Kommi, Pradeep S. Jadhavar, Dinesh Kumar, and Asit K. Chakraborti, “All water” one-pot diverse synthesis of 1,2-disubstituted benzimidazoles: hydrogen bond driven ‘synergistic electrophile-nucleophile dual activation’ by water,” Green Chem., 2013, 15, 798–810.
14) Damodara N. Kommi, Dinesh Kumar, Kapileswar Seth, and Asit K. Chakraborti, “Protecting group-free concise synthesis of (RS)/(S)-lubeluzole,” Org. Lett., 2013, 15, 1158–1161.
13) Dinesh Kumar, Kapileswar Seth, Damodara N. Kommi, Srikant Bhagat, and Asit K. Chakraborti, “Surfactant micelles as microreactors for the synthesis of quinoxalines in water: scope and limitations of surfactant catalysis,” RSC Adv., 2013, 3, 15157.
12) Dinesh Kumar, Damodara N. Kommi, Raj Kumar, and Asit K. Chakraborti, “Selectivity control during supported protic acid catalyzed synthesis of 1,2-disubstituted benzimidazoles and mechanistic insight to rationalize selectivity,” RSC Adv., 2013, 3, 91-98.
11) Dinesh Kumar, N. Kommi, Alpesh R. Patel, and Asit K. Chakraborti “Catalytic procedures for multicomponent synthesis of imidazoles: Selectivity control during the competitive formation of tri- and tetra-substituted imidazoles,” Green Chem., 2012, 14, 2038-2049.
10) Damodara N. Kommi, Dinesh Kumar, Rohit Bansal, Rajesh Chebolu, and Asit K. Chakraborti, “All-water chemistry of tandem N-alkylation–reduction–condensation for synthesis of N-arylmethyl-2-substituted benzimidazoles,” Green Chem., 2012, 14, 3329-3335.
9) Rajesh Chebolu, Damodara N. Kommi, Dinesh Kumar, Narendra Bolleneni, and Asit K. Chakraborti, “Hydrogen-bond driven electrophilic activation for selectivity control: the scope and limitations of fluorous alcohol promoted selective formation of 1,2-disubstituted benzimidazoles and mechanistic insight for rational of selectivity,” J. Org. Chem., 2012, 77, 10158–10167.
8) Dinesh Kumar, Damodara. N. Kommi, Pradeep Chopra, Md. Imam Ansari, and Asit K. Chakraborti, “L-Proline-catalyzed activation of methyl ketones or active methylene compounds and DMF-DMA for syntheses of (2E)-3-dimethylamino-2- propen-1-ones,” Eur. J. Org. Chem., 2012, 6407–6413.
7) Anirban Sarkar, Sudipta Raha Roy, Dinesh Kumar, Chetna Madaan, Santosh Rudrawar, and Asit K. Chakraborti, “Lack of correlation between catalytic efficiency and basicity of amines during the reaction of aryl methyl ketones with DMF-DMA: supramolecular domino catalysis,” Org. Biomol. Chem., 2012, 10, 281-286.
6) Naisargee Parikh, Dinesh Kumar, Sudipta Raha Roy, and Asit K. Chakraborti, “Surfactant mediated oxygen reuptake in water for green aerobic oxidation: mass-spectrometric determination of discrete intermediates to correlate oxygen uptake with oxidation efficiency,” Chem. Commun., 2011, 47, 1797-1799.
5) Sachin Bindal, Dinesh Kumar, Damodara N. Kommi, Sonam Bhatiya, and Asit K. Chakraborti, “Efficient organocatalytic dual activation strategy for preparation of the versatile synthons 2(E)-1-(het)aryl/styryl-3-(dimethylamino)prop-2-en-1-ones and α-(E)- [(dimethylamino)methylele]cycloalkanones,” Synthesis, 2011, 1930-1935.
4) Asit K. Chakraborti, Sudipta Raha Roy, Dinesh Kumar, and Pradip Chopra, “Catalytic application of room temperature ionic liquids for sustainable development: Butylmethylimidazolium sulfate ([bmim][MeSO4]) as a novel and recyclable catalyst for the synthesis of bis-indolylmethanes,” Green Chem., 2008, 10, 1111–1118.
3) Dinesh Kumar, Raj Kumar, and Asit K. Chakraborti “Tetrafluoroboric acid adsorbed on silica gel as a reusable heterogeneous dual-purpose catalyst for conversion of aldehydes/ketones into acetals/ketals and back again,” Synthesis, 2008, 1249–1256.
2) Dinesh Kumar, Santosh Rudrawar, and Asit K. Chakraborti “One-Pot synthesis of 2-substituted benzoxazoles directly from carboxylic acids,” Aust. J. Chem., 2008, 61, 881–887.
1) Raj Kumar, Dinesh Kumar, and Asit K. Chakraborti, “Perchloric acid adsorbed on silica gel (HClO4–SiO2) as an inexpensive, extremely efficient, and reusable dual catalyst system for acetal/ketal formation and their deprotection to aldehydes/ketones,” Synthesis, 2007, 0299–0303.
No synonyms found.
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